NOT KNOWN FACTS ABOUT CONOLIDINE ALKALOID FOR CHRONIC PAIN

Most just lately, it's been identified that conolidine and the above mentioned derivatives act around the atypical chemokine receptor 3 (ACKR3. Expressed in similar locations as classical opioid receptors, it binds to some wide array of endogenous opioids. As opposed to most opioid receptors, this receptor acts to be a scavenger and would not activ